| North Carolina State Wolfpack Football vs. East Carolina Pirates | 8-28-2025
Thursday
TBD | Carter Finley Stadium in Raleigh, NC | View Tickets |
| East Carolina Pirates Football vs. Campbell Fighting Camels | 9-6-2025
Saturday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| Coastal Carolina Chanticleers Football vs. East Carolina Pirates | 9-13-2025
Saturday
TBD | Brooks Stadium in Conway, SC | View Tickets |
| East Carolina Pirates Football vs. BYU Cougars | 9-20-2025
Saturday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| East Carolina Pirates Football vs. Army West Point Black Knights | 9-25-2025
Thursday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| Tulane Green Wave Football vs. East Carolina Pirates | 10-9-2025
Thursday
TBD | Yulman Stadium in New Orleans, LA | View Tickets |
| East Carolina Pirates Football vs. Tulsa Golden Hurricane | 10-16-2025
Thursday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| Temple Owls Football vs. East Carolina Pirates | 11-1-2025
Saturday
TBD | Lincoln Financial Field in Philadelphia, PA | View Tickets |
| East Carolina Pirates Football vs. Charlotte 49ers | 11-8-2025
Saturday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| East Carolina Pirates Football vs. Memphis Tigers | 11-15-2025
Saturday
TBD | Dowdy-Ficklen Stadium in Greenville, NC | View Tickets |
| UTSA Roadrunners Football vs. East Carolina Pirates | 11-22-2025
Saturday
TBD | Alamodome in San Antonio, TX | View Tickets |
| Florida Atlantic Owls Football vs. East Carolina Pirates | 11-29-2025
Saturday
TBD | Flagler Credit Union Stadium in Boca Raton, FL | View Tickets |
